Gamolenic acid
Brand names Efamast, Epogam, Gamolin, Gamophase
Used in the following combined preparations
Many preparations containing evening primrose oil, including Efamol and EPOC
GENERAL INFORMATION
Gamolenic acid is an essential fatty acid that is found in evening primrose oil and starflower oil (borage oil). Essential fatty acids are found in some foods and are necessary for full health. The beneficial effects of evening primrose oil include improving the hair and skin condition and strengthening the nails. Essential fatty acids have numerous functions and contribute to the manufacture of cells and certain important chemicals, such as prostaglandins. Administration of gamolenic acid enhances production of these chemicals in the body.
The drug has been investigated for use for a variety of conditions, including multiple sclerosis and premenstrual syndrome. Gamolenic acid may also be obtained by prescription for treating eczema and breast pain.
QUICK REFERENCE
Overdose danger rating Low
Dependence rating Low
Prescription needed No
Available as generic No
INFORMATION FOR USERS
Follow Instructions on the label. Call your doctor if symptoms worsen.
How taken
Capsules, liquid.
Frequency and timing of doses
If desired, 2 x daily. The capsules may be cut open and the contents swallowed.
Adult dosage range
Epogam 8-12 capsules daily (eczema); Efamast 6-8 capsules daily (breast pain). For other brands, follow the instructions on the packet. Onset of effect
Normally 8-12 weeks, but some effects may take longer. Duration of action
12-24 hours, although the beneficial effects will last longer.
Diet advice
None.
Storage
Keep in a closed container in a cool, dry, place out of the reach of children.
Missed dose
Take as soon as you remember. Stopping the drug
Symptoms may eventually recur if the drug is stopped.
Exceeding the dose
An occasional unintentional extra dose is unlikely to be a cause for concern. Large overdoses may cause loose faeces and abdominal pain. If you notice any unusual symptoms, or if a large overdose has been taken, notify your doctor.
POSSIBLE ADVERSE EFFECTS
Gamolenic acid does not usually cause problems with adverse effects.
SPECIAL PRECAUTIONS
Be sure to tell your doctor if:
You have a history of epilepsy.
You are taking other medications.
Pregnancy
Safety in pregnancy not established. Discuss with your doctor.
Breast-feeding
No known problems.
Infants and children
Not recommended under 1 year. Reduced dose necessary in older children.
Over 60
No special problems.
Driving and hazardous work
No known problems.
Alcohol
No known problems.
PROLONGED USE
No problems expected.
INTERACTIONS
Phenothiazines such as chlorpromazine and prochlorperazine
There may be an increased risk of convulsions in patients taking phenothiazines with gamolenic acid.
