Dicyclomine

Brand name Merbentyl

Used in the following combined preparations Diarrest, Koianticon

GENERAL INFORMATION

Dicyclomine is a mild anticholinergic antispasmodic drug that relieves painful abdominal cramps caused by spasm in the gastrointestinal tract. Used to treat irritable bowel syndrome, dicyclomine is also given to treat colicky conditions in babies.

Because the drug has anticholinergic properties, it is also included in some combined preparations used to treat flatulence, indigestion, and diarrhoea.

Dicyclomine relieves symptoms but does not cure the underlying condition.
Additional treatment with other drugs and self-help measures, such as dietary changes, may be recommended by your doctor.

INFORMATION FOR USERS

Your drug prescription is tailored for you. Do not alter dosage without checking with your doctor.

How taken

Tablets, liquid.

Frequency and timing of doses

3 x daily before or after meals.

Dosage range

Adults 30-60mg daily.

Children Reduced dose according to age and weight.

Onset of effect

Within 1-2 hours.

Duration of action

4-6 hours.

Diet advice

None.

Storage

Keep in a closed container in a cool, dry place out of the reach of children.
Protect from light.

Missed dose

Take as soon as you remember. If your next dose is due within 2 hours, take a single dose now and skip the next.

Stopping the drug

Do not stop the drug without consulting your doctor; symptoms may recur.

Exceeding the dose

An occasional unintentional extra dose is unlikely to cause problems. Large overdoses may cause drowsiness, dizziness, and difficulty in swallowing. Notify your doctor.

POSSIBLE ADVERSE EFFECTS

Most people do not notice any adverse effects when taking dicyclomine. Those that do occur are related to its anticholinergic properties and include drowsiness and dry mouth. Such symptoms may be overcome by adjusting the dosage, or they may disappear after a few days of usage as your body adjusts to the drug.

INTERACTIONS

Sedatives
All drugs that have a sedative effect on the central nervous system may increase the sedative properties of dicyclomine.

QUICK REFERENCE

Drug group Drug for irritable bowel syndrome

Overdose danger rating Medium

Dependence rating Low

Prescription needed Yes

Available as generic No

SPECIAL PRECAUTIONS

Be sure to tell your doctor if:

You have glaucoma.

You have urinary problems. You have hiatus hernia.

You are taking other medications.

Pregnancy

No evidence of risk.

Breast-feeding

The drug passes into the breast milk, but at normal doses adverse effects on the baby are unlikely. Discuss with your doctor.

Infants and children

Reduced dose necessary.

Over 60

Reduced dose necessary. The elderly are more susceptible to anticholinergic side effects.

Driving and hazardous work

Avoid such activities until you have learned how dicyclomine affects you because the drug can cause drowsiness and blurred vision.

Alcohol

Avoid. Alcohol may increase the sedative effects of this drug.

PROLONGED USE

No problems expected.

May 12, 2011 · Posted in Practical advice for non-medical people  
    

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