Brand names None
Used in the following combined preparations Otrivine-Antistin, R.B.C.
General Information
Antazoline is an antihistamine drug that can be bought over the counter as an
ingredient of a variety of topical preparations. Eye drops containing the drug
are used to relieve irritation caused by allergic conjunctivitis. The drug is
also applied to the skin in the form of a cream for the relief of itching and
irritation caused by insect bites or allergic rashes.
Adverse effects from the drug are rare. Continuous use for longer than a few
days should be avoided, as there is a risk of allergy developing with all
topical antihistamines.
Information For Users
Follow instructions on the label. Call your doctor if symptoms worsen.
How taken
Cream, eye drops.
Frequency and timing of doses
Every 3-6 hours, depending on preparation.
Adult dosage range
Varies according to preparation.
Onset of effect
Within a few minutes.
Duration of action
Up to 6 hours.
Diet advice
None.
Storage
Keep in a closed container in a cool, dry place out of the reach of children.
Missed dose
No cause for concern. Use only when needed. Stopping the drug
Can be safely stopped as soon as you no longer need it.
Exceeding the dose
An occasional unintentional extra application is unlikely to be a cause for
concern. But if you notice unusual symptoms, or if a large amount has been
swallowed, notify your doctor.
Possible Adverse Effects
Antazoline is less likely to cause irritation than other antihistamines used in
topical preparations.
Quick Reference
Drug group Antihistamine
Overdose danger rating Low
Dependence rating Low
Prescription needed No
Available as generic No
Special Precautions
Be sure to consult your doctor or pharmacist before taking this drug if:
You have glaucoma.
You have angina or high blood pressure.
You wear contact lenses (eye drops). You are taking other medications.
Pregnancy
No evidence of risk to developing baby.
Breast-feeding
No evidence of risk.
Infants and children
Not recommended under 5 years.
Over 60
No special problems.
Driving and hazardous work
No special problems.
Alcohol
No special problems.
Prolonged Use
Regular long-term use is not recommended.
