Review Drug

Brand names : Acetoxyl, Acnecide, Acnegel, Benoxyl, Nericur, Panoxyl

Used in the following combined preparations Acnidazil, Benzamycin, Quinoderm,
Quinoped

GENERAL INFORMATION

Benzoyl peroxide is used in a variety of topical preparations for the treatment
of acne and some fungal skin infections, particularly of the feet. Available
over the counter, it comes in concentrations of varying strengths for moderate
acne.

Benzoyl peroxide works by removing the top layer of skin and unblocking the
sebaceous glands. The drug reduces inflammation of blocked hair follicles by
killing bacteria that infect them.

Benzoyl peroxide may cause irritation due to its drying effect on the skin, but
this generally diminishes with time. The drug should be applied to the affected
areas as directed on the label. Washing the area prior to application greatly
enhances the drug’s beneficial effects. Side effects are less likely if
treatment is started with a preparation containing a low concentration of
benzoyl peroxide, and changed to a stronger preparation only if necessary.
Marked dryness and peeling of the skin, which may occur, can usually be
controlled by reducing the frequency of application. Care should be taken to
avoid contact of the drug with the eyes, mouth, and mucous membranes.
Preparations of benzoyl peroxide may bleach clothing.

INFORMATION FOR USERS

Follow instructions on the label. Call your doctor if symptoms worsen.

How taken

Cream, lotion, gel.

Frequency and timing of doses

1-2 x daily.

Dosage range

Apply sparingly to affected skin, as instructed on the label.

Onset of effect

Reduces oiliness of skin immediately. Acne usually improves within 4-6 weeks.

Duration of action

24-48 hours.

Diet advice

None.

Storage

Keep in a closed container in a cool, dry place out of the reach of children.

Missed dose

Apply as soon as you remember. Stopping the drug

Can be safely stopped as soon as you no longer need it.

Exceeding the dose

A single extra application is unlikely to cause problems. Regular overuse may
result in extensive irritation, peeling, redness, and swelling.

POSSIBLE ADVERSE EFFECTS

Application of benzoyl peroxide may cause temporary burning or stinging of the
skin. Redness, peeling, and swelling may result from excessive drying of the
skin and clear up if the treatment is stopped or used less frequently. If severe
burning, blistering, or crusting occur, stop using the product and consult your
doctor.

INTERACTIONS

Skin-drying preparations Medicated cosmetics, soaps, toiletries, and other
anti-acne preparations increase the likelihood of dryness and irritation of the
skin with benzoyl peroxide.

QUICK REFERENCE

Drug group Drug for acne and fungal skin infections

Overdose danger rating Low

Dependence rating Low

Prescription needed No

Available as generic No

SPECIAL PRECAUTIONS

Be sure to consult your doctor or pharmacist before using this drug if:

You have eczema.

You have sunburn.

You are taking other medications.

Pregnancy

No evidence of risk.

Breast-feeding

No evidence of risk.

Infants and children

Not recommended under 12 years except under medical supervision.

Over 60

Not usually required.

Driving and hazardous work

No known problems.

Alcohol

No known problems.

PROLONGED USE

Benzoyl peroxide should not be used for longer than 6 weeks except on the advice
of your doctor.